A string of injuries has changed that equation and left the 49ers with few proven options for Brock Purdy to throw the ball ...

Ahead of a visit from the Cowboys, 49ers head coach Kyle Shanahan is revealing the unfortunate news that Deebo Samuel is now ...

One division reflexed its muscles, and another went down with a whimper in our latest NFL Divisional Power Rankings.

This week’s 49ers mailbag is stocked with questions (and answers) regarding their offensive shortcomings, fourth-quarter ...

San Francisco 49ers head coach reveals Deebo Samuel is dealing with a tough condition. Kyle Shanahan says there's no timeline ...

Chiefs, provides injury updates “San Francisco 49ers head coach Kyle Shanahan spoke with reporters during a conference call ...

Following the significant losses of players due to injury and illness, including Brandon Aiyuk, San Francisco 49ers head ...

And yet Kyle Shanahan treated it like he treats all games: He played not to lose. So the 49ers lost.

Already missing star running back Christian McCaffrey to Achilles tendinitis in both his calves, the team also lost star wideouts Deebo Samuel and Brandon Aiyuk during Sunday's 28-18 loss to the ...

The first year of Aiyuk's $120 million four-year contract extension, which was marked by a long dispute with the 49ers, ...

The San Francisco 49ers were hit with a double dose of rough health news regarding two wide receivers on Monday. First, the ...