Reggie Watts is at his best on stage, making up songs and jokes on-the-spot. He says an improvisational spirit can turn the mundanity of daily life into an adventure.

In the 90s, Kristine Tompkins and her late husband began buying swaths of land in South America. Their plan to create national parks through private enterprise had no precedent. That didn't stop them.

When Sonia Vallabh learned she has the genetic mutation for prion disease, she and her husband dropped everything to change careers. Today, they lead a Harvard/MIT lab searching for a cure.

How does the killing of Hamas leader Yahya Sinwar change the prospects for a negotiation with Israel, and what is the next step for Hamas? NPR's Leila Fadel talks with Khaled Elgindy, senior fellow at ...